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Synthesis and some characteristics of no-carrier added [18F]fluorotrimethylsilane

โœ Scribed by M.S. Rosenthal; A.L. Bosch; R.J. Nickles; S.J. Gatley


Book ID
107769359
Publisher
Elsevier Science
Year
1985
Weight
214 KB
Volume
36
Category
Article
ISSN
0020-708X

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3-N-([18F]fluoroalkyl)spiperone derivatives (2,3) can be prepared by N-alkylation of spiperone (1) with fluoroalkyl halides. The fluoroalkylating species 2-[18F]fluoroethyl bromide (7), 3-[18F]fluoropropyl bromide (8) and 4-[18F]fluorobutyl bromide (9) were prepared by [18F]fluoride ion displacement