Synthesis and Solution Conformation of β-Hairpin Mimetics Utilizing a Template Derived from (2S,3R,4R)-Diaminoproline

ChemInform Abstract: A Tricyclic Templat

ChemInform Abstract: A Tricyclic Template Derived from (2S,4R)-4-Hydroxyproline for the Synthesis of Protein Loop Mimetics.

✍ R. BEELI; M. STEGER; A. LINDEN; J. A. ROBINSON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

A Tricyclic Template Derived from (2S,4R)-4-Hydroxyproline for the Synthesis of Protein Loop Mimetics. -Starting from (2S,4R)-4hydroxyproline the tricyclic diketopiperazine ( VI) is synthesized. This template has carboxy and amino groups to which a peptide chain may be attached. By investigations w