Synthesis and SAR evaluation of oxadiazo
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Xenia Beebe; Angela M. Nilius; Philip J. Merta; Niru B. Soni; Mai H. Bui; Rolf W
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Article
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2003
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Elsevier Science
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English
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The parallel synthesis and antibacterial activity of 5-hydroxy[1,2,5] oxadiazolo[3,4-b]pyrazines is reported. The compounds were synthesized by condensing diaminofurazan with alpha-keto acids to give a variety of aryl-substituted analogues. Halogenated phenyl groups at C-6 give rise to the greatest