Synthesis and release of platelet-activating factor and eicosanoids in human endothelial cells induced by different agonists
✍ Scribed by F. Cabré; D. Tost; N. Suesa; M. Gutiérrez; P. Ucedo; D. Mauleón; G. Carganico
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1993
- Tongue
- English
- Weight
- 624 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Platelet-activating-factor (PAF) is a potent, biologically active lipid mediator produced by several tissues, including brain. Its role in the central nervous system (CNS) is still unknown, even if its involvement in brain damage and neurotoxicity has been postulated. Its production by neural cells
We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated
Programmed cell death contributes to the morbidity and mortality of several neurological disorders including stroke, Alzheimer's disease and human immunodeficiency virus (HIV)-associated dementia. Patients with HIV dementia show evidence of programmed cell death in brain. In vitro data demonstrates
Stimulation of interleukin-1 (11-1) in peripheral blood monocytes exposed to Creactive protein (CRP) and C-reactive protein-platelet-activating factor (CRP-PAF) complexes was demonstrated in vitro in this study. Significant synthesis of intracellular IL-l12-5-foId increases in the number of adherent