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S35b, a new phenylsulfonylfuroxan compound, inhibits thrombin-induced synthesis of platelet-activating factor and prostacyclin in human endothelial cells

✍ Scribed by R. Heller; F. Bussolino; R. Calvino; D. Ghigo; P. Alessio; R. Todde; R. Fruttero; G. Pescarmona; A. Gasco; U. Till; A. Bosia


Publisher
SP Birkhäuser Verlag Basel
Year
1993
Tongue
English
Weight
838 KB
Volume
40
Category
Article
ISSN
1420-908X

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To characterize the endothelial cell surface membrane glycoproteins that mediate thrombin stimulation of PGI2 synthesis by human umbilical vein endothelial cells (HUVEC), HUVEC were stimulated with thrombin in the presence or absence of different lectins. Of the lectins tested, only wheat germ agglu