𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and reduction of endothiodipeptides containing malonic acid derivatives

✍ Scribed by Dirk Krumme; Harald Tschesche

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
702 KB
Volume
55
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

Amides of malonic acid derivatives and protected dipeptides containing amino malonic acid have been synthesized and converted into the corresponding monothio analoga and andothiodipeptides. By reduction of the thioamides terminal protected [5-carboxy amino derivatives were obtained. Reduction of endothiodipcptides containing amino malonic acid as the carboxy component resulted in protected ~P[CH2NH] pseudodipeptides fer the use as dipeptide substitutes with proteolytic resistance.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Microwave Heating i
ChemInform Abstract: Microwave Heating in Organic Synthesis: Decarboxylation of Malonic Acid Derivatives in Water.
✍ Cynthia Lynn Zara; Thomas Jin; Raymond J. Giguere πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons βš– 27 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Solid phase synthesis of benzothiazole a
Solid phase synthesis of benzothiazole and thiophene derivatives based on resin-bound cyclic malonic acid ester
✍ Xian Huang; Jing Tang πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 308 KB

A new method for the solid phase synthesis of benzothiazoles and 2-arylamino-3-carboxyl-4-hydroxy-5-arylthiophenes is described. Resin bound cyclic malonic acid ester was reacted with aryl isothiocyanates and then with bromine or a-bromoketones, followed by treatment with perchloric acid or sodium m