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Synthesis and redox-enzyme modulation by amino-1,4-dihydro-benzo[d][1,2]dithiine derivatives

✍ Scribed by Sandraliz Espinosa; Melissa Solivan; Cornelis P. Vlaar

Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
948 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis

A convenient method to prepare a series of benzodithiine derivatives was developed, via the synthesis of cyclic disulfide building blocks containing an amino-group linker. Some of the novel cyclic disulfide compounds are shown to modulate the activity of the redox-enzyme glutathione reductase.

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