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Synthesis and receptor binding of oxytocin analogs containing conformationally restricted amino acids

✍ Scribed by Krisztina Bakos; Judit Havass; Ferenc Fülöp; Lajos Gera; John M. Stewart; George Falkay; Gábor K. Tóth

Book ID
110327507
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
80 KB
Volume
8
Category
Article
ISSN
1573-3149

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The synthesis of 5,6-bicyclic thymine:thymine nucleoside containing a conformationally restricted dioxane acetal has been achieved from 2'-O-allyl 5-methyl uridine. The two diastereomers were separated and incorporated in a single position within an oligonucleotide (ON) sequence. The binding propert