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Synthesis and reactivity of 4-substituted-2,3-dihydrobenzo-1,4-thiazines

✍ Scribed by Saverio Florio; John L. Leng; Charles J. M. Stirling


Book ID
112126677
Publisher
Journal of Heterocyclic Chemistry
Year
1982
Tongue
English
Weight
328 KB
Volume
19
Category
Article
ISSN
0022-152X

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Depending on the reaction conditions eithcr 2.6-disubstitutcd 2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones 4 or 1,6-disubstitutcd 2-thiouracils 5 are readily prepared by base-catalyzcd cyclization of N-propenoylthioureas 3. Compounds 5 could also bc obtained by Dimroth-type rearrangement of 1,3-thiazin-