Facile synthesis of 2-(substituted amino)-4H-thieno[3,2-e]-1,3-thiazin-4-ones
✍ Scribed by Rajab Abu-El-Halawa; Alaa Sarabi; Mustafa M. El-Abadelah
- Book ID
- 106214235
- Publisher
- Springer Vienna
- Year
- 2008
- Tongue
- English
- Weight
- 153 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0026-9247
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Depending on the reaction conditions eithcr 2.6-disubstitutcd 2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones 4 or 1,6-disubstitutcd 2-thiouracils 5 are readily prepared by base-catalyzcd cyclization of N-propenoylthioureas 3. Compounds 5 could also bc obtained by Dimroth-type rearrangement of 1,3-thiazin-
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