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Synthesis and reactions of 3-diazo-1,4-diphenyl-4-hydroxy-2-butanone

✍ Scribed by Woolsey, Neil F.; Khalil, Mohammed H.


Book ID
126980066
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
542 KB
Volume
37
Category
Article
ISSN
0022-3263

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## ABSTRACT Enantioselective syntheses of two stereoisomers of 3‐hydroxy‐4‐phenyl‐2‐butanone were investigated via Shi's asymmetric epoxidation or Sharpless asymmetric dihydroxylation of silyl enol ether. (__R__)‐3‐Hydroxy‐4‐phenyl‐2‐butanone was obtained in 73% enantiomeric excess (__ee__) by Shi'