Synthesis and reactions of 2-deoxy-β-D-ribofuranosyl derivatives of 3-aryl-4H-pyrrolo[2,3-d]pyrimidin-4-imines
✍ Scribed by M. A. Zahran; E. B. Pedersen; C. Nielsen
- Publisher
- Springer Vienna
- Year
- 1995
- Tongue
- English
- Weight
- 457 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0026-9247
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## Abstract The title compounds **2** were prepared by treating 2‐(acetylamino)‐3‐pyrrolecarbonitriles **1** with a mixture of phosphorus pentoxide, __N,N__‐dimethylcyclohexanamine, and an appropriate arylamine hydrochloride at 150–180°C. The importance of using absolutely anhydrous arylamine hydro
## Abstract The synthesis of the 3‐ and 4‐(methylthio)pyrazolo[3,4‐__d__]pyrimidine N^1^‐ and N^2^‐2′‐deoxy‐β‐D‐ribonucleosides 2b, 15 is described. Anionic glycosylation of 5‐amino‐3‐(methylthio)‐4‐pyrazolecarbonitrile (4) or 4‐(methylthio)pyrazolo[3,4‐__d__]pyrimidine (12) with 2‐deoxy‐3,5‐di‐__O