## Abstract Ten arylβcarbohydrate ligands have been synthesized that potentially increase the tumor retention and decrease the deiodination of iodinated monoclonal antibodies used in the imaging and treatment of cancer. The compounds were synthesized via reductive amination reactions, purified with
Synthesis and radioiodinatton of aryl-carbohydrate compounds for attachment to monoclonal antibodies
β Scribed by S.A. Ali; S.D. Warren; C.C. Badger; J.F. Eary; O.W. Press; K. A. Krohn; W. B. Nelp
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 151 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-2135
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π SIMILAR VOLUMES
The synthesis of new linked bis-and tris-ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorporating a dioxocyclam ring is also reported.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v