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Synthesis and radical scavenging activity of 3,3-dialkyl-3,4-dihydro-isoquinoline 2-oxides

✍ Scribed by Ronald C. Bernotas; Craig E. Thomas; Albert A. Carr; Thaddeus R. Nieduzak; Ginette Adams; David F. Ohlweiler; David A. Hay


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
275 KB
Volume
6
Category
Article
ISSN
0960-894X

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## Abstract Novel 3 substituted 1,5‐dihydro‐2,4,3‐benzodioxaphosphepine 3‐oxides (**5a–h**) were synthesized by reacting 1,2‐benzenedimethanol (**1**) with phosphorus tribromide in the presence of triethylamine at 0–30Β°C and subsequent reaction of the monobromide (**2**) with different Grignard rea