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Synthesis and Quantitative Structure−Activity Relationships of New 2,5-Disubstituted-1,3,4-oxadiazoles

✍ Scribed by Shi, Wei; Qian, Xuhong; Zhang, Rong; Song, Gonghua


Book ID
120082941
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
107 KB
Volume
49
Category
Article
ISSN
0021-8561

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✍ Fouad Bentiss; Michel Lagrenée 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 182 KB 👁 1 views

## Abstract Several new 2,5‐disubstituted 1,3,4‐oxadiazoles have been synthesized in good yields by reaction of aromatic acids with hydrazine dihydrochloride in a mixture of orthophosphoric acid, phosphorus pentoxide and, in general, with addition of phosphorus oxychloride to the reaction mixture.