Pyrene-Modified Unlocked Nucleic Acids:
Pyrene-Modified Unlocked Nucleic Acids: Synthesis, Thermodynamic Studies, and Fluorescent Properties
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Dr. Kasper K. Karlsen; Dr. Anna Pasternak; Dr. Troels B. Jensen; Prof. Dr. Jespe
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Article
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2012
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John Wiley and Sons
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English
⚖ 988 KB
## Abstract Two pyrene‐modified UNA monomers were synthesized and incorporated into 21‐mer DNA oligonucleotides. Melting temperatures and thermodynamic properties of the modified duplexes were measured, and the fluorescence properties of single strands and duplexes containing one or more pyrene‐UNA