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Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate)

✍ Scribed by Eckstein, Fritz; Goody, Roger S.


Book ID
126803232
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
775 KB
Volume
15
Category
Article
ISSN
0006-2960

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## Abstract Treatment of adenosine with PSCl~3~ in trimethyl phosphate gave, after ion‐exchange chromatography, adenosine‐5′‐__O__‐monophosphate (AMP; 28%) and adenosine‐5′‐__O__‐monothiophosphate (AMPS; 48%). AMPS was studied as a thiophosphate residue donor in an enzymatic transphosphorylation wi