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Enzymatic Synthesis of Nucleoside-5′-O-(1-thiophosphates) and (SP)-Adenosine-5′-O-(1-thiotriphosphate).

✍ Scribed by Vladimir N. Barai; Anatoli I. Zinchenko; Sergei V. Kvach; Olga I. Titovich; Elena B. Rubinova; Elena N. Kalinichenko; Igor A. Mikhailopulo

Book ID
101952337
Publisher
John Wiley and Sons
Year
2003
Weight
86 KB
Volume
34
Category
Article
ISSN
0931-7597

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Enzymatic Synthesis of Nucleoside-5′-O-(
Enzymatic Synthesis of Nucleoside-5′-O-(1-thiophosphates) and (SP)-Adenosine-5′-O-(1-thiotriphosphate)
✍ Vladimir N. Barai; Anatoli I. Zinchenko; Sergei V. Kvach; Olga I. Titovich; Elen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 92 KB

## Abstract Treatment of adenosine with PSCl~3~ in trimethyl phosphate gave, after ion‐exchange chromatography, adenosine‐5′‐__O__‐monophosphate (AMP; 28%) and adenosine‐5′‐__O__‐monothiophosphate (AMPS; 48%). AMPS was studied as a thiophosphate residue donor in an enzymatic transphosphorylation wi