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Synthesis and Properties of an Oligonucleotide Modified with an Acridine Derivative at the Artificial Abasic Site

✍ Scribed by Fukui, Keijiro; Morimoto, Minoru; Segawa, Hiroshi; Tanaka, Kazuyoshi; Shimidzu, Takeo

Book ID
120224652
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
187 KB
Volume
7
Category
Article
ISSN
1043-1802

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Solid-phase synthesis of modified oligod
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## Use of a derivatized support involving the 2,2'-diethyldithio-group 1 SllOWS the automated synthesis of oligodeoxyribonucleotide bearing acridine derivative (via nucleoside-3'acridinylphosphoramidite 2) or 3'phosphorothioate group (including the sulfurization step fOJ2 attachment of the first n