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Synthesis and Properties of 2‘-Deoxy-2‘-α- C -branched Nucleosides and Nucleotides

✍ Scribed by Lawrence, Anthony J.; Pavey, John B. J.; Cosstick, Richard; O'Neil, Ian A.


Book ID
126792718
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
377 KB
Volume
61
Category
Article
ISSN
0022-3263

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Synthesis of (2′S)-2′-Deoxy-2′-C-methylp
✍ Gerardo Caballero; Mariana Gallo; Javier M. Montserrat; Adolfo M. Iribarren 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 154 KB 👁 2 views

We describe the stereoselective synthesis of (2'S)-2'-deoxy-2'-C-methyladenosine ( ) and (2'S)-2'-deoxy-2'-C-methylinosine ( ) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-O-(2,6dichlorophenyl)inosine as starting material. The methyl group at the 2'-position was introd