Synthesis and preliminary evaluation of para- and meta-[18F]fluorobenzylguanidine
β Scribed by Garg, Pradeep K.; Garg, Sudha; Zalutsky, Michael R.
- Book ID
- 122548644
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 815 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0969-8051
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π SIMILAR VOLUMES
2-1eF-phenylalanine and 3-leF-tyrosine were synthesized by direct electro hilic substitution of L-phenylalanine and Ltyrosine with PeF-acetylhypofluorite. obtained in 30 % radiochemical yield based on l$F-acetylhypofluorite within 60 min after the end of irradiation. In rat brain, 30 % of the radioa
## Abstract ^18^Fβlabeled fluorobenzaldehydes and fluorobenzylbromides are useful synthons for the preparation of positron emission tomography radiopharmaceuticals. Although __orthoβ__ and __paraβ__[^18^F]fluorobenzaldehydes can easily be prepared with high yields, the corresponding __metaβ__deriva