𝔖 Bobbio Scriptorium
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Synthesis and preliminary evaluation of a new quinuclidine derivative as a radioprotective agent

✍ Scribed by Warren Shapiro; Martin F. Tansy; Samuel Elkin

Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
349 KB
Volume
57
Category
Article
ISSN
0022-3549

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✦ Synopsis

Sprague-Dawley rats 50 days old induced breast tumors within 21-120 days of feeding. When testing against these tumors, 9-methoxyellipticine was found to be inactive at 30 mg./kg. i.p. and 60 mg./ kg. per 0s. Furthermore, some weight loss and toxicity were evidenced in both regimens.

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