𝔖 Bobbio Scriptorium
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Synthesis and Evaluation of a New Ganglionic Blocking Agent*

✍ Scribed by Schueler, F.W ;Keasling, H.H


Publisher
Elsevier
Year
1954
Weight
378 KB
Volume
43
Category
Article
ISSN
0095-9553

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Synthesis and preliminary evaluation of
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Sprague-Dawley rats 50 days old induced breast tumors within 21-120 days of feeding. When testing against these tumors, 9-methoxyellipticine was found to be inactive at 30 mg./kg. i.p. and 60 mg./ kg. per 0s. Furthermore, some weight loss and toxicity were evidenced in both regimens.