To develop a small molecule-based biomarker for in vivo apoptosis imaging, a dansyled amino acid derivative (BNSBA) was designed and synthesized in good yield. The biological evaluation demonstrated that BNSBA selectively binds to apoptotic cancer cells and is localized within the cytoplasm of cells
✦ LIBER ✦
Synthesis and physical properties of a novel aminophosphonic acid as an extracting agent for metals
✍ Scribed by V. Jagodić; M.J. Herak
- Book ID
- 118907800
- Publisher
- Elsevier Science
- Year
- 1970
- Weight
- 386 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-1902
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## Abstract A major drawback of conventionally radioiodinated monoclonal antibodies for radioimmunotherapy is __in vivo__ dehalogenation of iodine as a result of deiodinase recognition. To solve this problem we have synthesized a YYK tri‐peptide consisting of non‐metabolizable D‐amino acids modifie