Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds
β Scribed by V. K. Tandon; Meenu Vaish; J. M. Khanna; Nitya Anand
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 227 KB
- Volume
- 323
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
β¦ Synopsis
Series of (1.4)-Naphthoquinono(3,2-c>lH-pyrazoles and 2-substituted amino-1.4-naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Wulker 256 carcinosarmma). MluenZa RNA tmnscriptase activity, ,antibiotic activity (C. neoformans, T. mentagraphytes. M . canis, A. niger, and C. albicans). 1,4-Naphthochinon[3,2-~]-1H-pyrazole and 2-substituierte Arnino-1,4naphthochinone wurden hergestellt und auf cytostatische Wirkung (Tiertu-
π SIMILAR VOLUMES
and 3-aminopyrazole and 3-amino-1,2,4-triazole provide convenient access to biologically relevant 3H-imidazo[1,2-b]pyrazoles and a 5H-imidazo[2,1-c][1,2,4]triazole.
Synthesis and Dopaminergic Properties of 3-and 4-Substituted 1-(2-(5-( 1H-Benzimidazole-2-thione))ethyl)piperidines and Related Compounds. -Among a series of title compounds, e.g. (I), especially compound (Ia) and its (+)-enantiomer behave as selective high affinity D2 receptor ligands. Only some o