Synthesis and pharmacological evaluation of some new dibenzo [b, f] [1, 4]thiazepines
✍ Scribed by Pawar, Sarita; Roy, Akhilesh; Wagh, Sanjay
- Book ID
- 122283778
- Publisher
- Elsevier
- Year
- 2013
- Tongue
- English
- Weight
- 384 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0974-6943
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## Abstract The S‐amination of 9__H__‐thioxanthen‐9‐ol (**2a**) and 9‐substituted derivatives **2b**–**e** (Me (**b**), Et (**c**), ^i^Pr (**d**), Ph (**e**)) with O‐mesitylenesulfonylhydroxylamine (MSH) was carried out. The expected product, 10‐amino‐9‐hydroxy‐9‐isopropyl‐9__H__‐thioxanthenium mes
## Abstract magnified image A convenient synthesis of the novel dibenzo[__b,f__][1,4]thiazepin‐11(10__H__)‐ones is reported. As a key step, the synthetic route includes intramolecular aromatic denitrocyclization of 2‐(2,4‐dinitro‐phenylsulfanyl)‐benzoic acid amides. Efficient procedures for denitr