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Synthesis and Pharmacological Evaluation of N-Phenyl-N′-[1-[3-(1-aryl-4-piperazinyl)propan-2-ol]]ureas

✍ Scribed by Jean Jacques Bosc; Christian Jarry


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
34 KB
Volume
331
Category
Article
ISSN
0365-6233

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Tritiated N,N'-dibenzoyl-l,3-diaminopropan-2-ol, a compound mimicking a diacylglycerol moiety used as a lipid drug carrier was prepared from N,N'-dibenzoyl-l,3-diaminopropan-2-o1 by isotopic exchange in the presence of rhodium chloride. Preliminary preparation of the deuterated analog was made in o