Synthesis and Pharmacological Characterization of Bivalent Ligands of Epibatidine at Neuronal Nicotinic Acetylcholine Receptors
β Scribed by Zhi-Liang Wei; Yingxian Xiao; Kenneth J. Kellar; Alan P. Kozikowski
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 83 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image A group of novel 4,5βdihydroβ3βmethylisoxazolyl derivatives, structurally related to epiboxidine (=(1__R__,4__S__,6__S__)β6β(3βmethylisoxazolβ5βyl)β7βazabicyclo[2.2.1]heptane), was prepared __via__ 1,3βdipolar cycloaddition of acetonitrile oxide to different olefins. Ta