Synthesis and pharmacological activity of 1-(4-substituted phenyl)-1-alkyl(aryl)-3-piperidinopropanol hydrochlorides
β Scribed by N. K. Gasparyan; R. G. Paronikyan; A. E. Tumadzhyan; A. A. Tatevosyan; G. A. Panosyan; G. A. Gevorgyan
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 79 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0091-150X
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π SIMILAR VOLUMES
Mono-Mannich bases, 1-aryl-3-phenethylamino-1-propanone hydrochlorides, 1a, 2a, 3a, 4a, 5a, 6a, 7a, 8a, 9a, and semi-cyclic mono-Mannich bases, 3-aroyl-4-aryl-1-phenethyl-4-piperidinols, 1b, 2b, 3b, 4b, 5b, 6b, 7b, 8b, 9b, were synthesized by a non-classical Mannich reaction. The aryl part was: C(6)
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## Abstract magnified image Cyclocondensation of 2βacylphenylacetonitriles **1** with amines affords 1βsubstituted 3βaminoisoquinolines **2** in good yields.