ChemInform Abstract: Synthesis and Pharmacological Activity of 1-Substituted 5-Aryl-4-acyl-3-hydroxy-3-pyrrolin-2-ones.
โ Scribed by V. L. GEIN; ET AL. ET AL.
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
Simple Three-Component Synthesis of 4-Acyl-5-phenyl-1-(2-hetaryl)-3-hydroxy-3-pyrrolin-2-ones. -Thermal three-component cyclocondensation of methyl acylpyruvate (I), benzaldehyde (II) and hetarylamines (III) furnishes the novel 4-acyl-5-phenylpyrrolinones-2 (IV) containing a hetaryl group at the N(
Synthesis and Pharmacological Activity of 2-(Substituted Phenyl)-3-(2 or 3-((4-Substituted Phenyl-4-hydroxy)piperidino)ethyl or propyl)-1,3-thiazolidin-4-ones. -A new series of 1,3-thiazolidinone analogues of loperamide (cf. (IV), 10 examples) are synthesized and evaluated for their antidiarrheal a