✦ LIBER ✦

Synthesis and pet-studies of (R)-and (S)-[11C]verapamil for measuring PGP function in MDR1A(+/+)/B(+/+) and MDR1A(-/-)/B(-/-) mice

✍ Scribed by G. Luurtsema; A. D. Windhorst; J. D. M. Herscheid; C. F. M. Molthoff; R. Boellaard; H. Smit; A. H. Schinkel; A. A. Lammertsma; E. J. F. Franssen

Book ID: 112132552
Publisher: John Wiley and Sons
Year: 2001
Tongue: French
Weight: 202 KB
Volume: 44
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.25804401110

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics of irinotecan (CPT-11)

Pharmacokinetics of irinotecan (CPT-11) in wildtype-and P-glycoprotein- (P-gp) knockout (mdr1a/1b (−/−)) mice

✍ U. Mayer; B. Mueller; D.K. Hossfeld 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 184 KB

(R)- and (S)-[11C]verapamil as PET-trace

(R)- and (S)-[11C]verapamil as PET-tracers for measuring P-glycoprotein function: in vitro and in vivo evaluation

✍ G Luurtsema; C.F.M Molthoff; A.D Windhorst; J.W Smit; H Keizer; R Boellaard; A.A 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 137 KB

Synthesis of [11C]dehydropravastatin, a

Synthesis of [11C]dehydropravastatin, a PET probe potentially useful for studying OATP1B1 and MRP2 transporters in the liver

✍ Ryosuke Ijuin; Tadayuki Takashima; Yasuyoshi Watanabe; Yuichi Sugiyama; Masaaki 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 626 KB

Fully automated high yield synthesis of

Fully automated high yield synthesis of (R)- and (S)-[11C]verapamil for measuring P-glycoprotein function with positron emission tomography

✍ Gert Luurtsema; Albert D. Windhorst; Martien P.J. Mooijer; Jacobus D.M. Herschei 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 118 KB 👁 1 views

## Abstract Racemic (±) verapamil is a well characterized substrate for P‐glycoprotein (P‐gp). However, the __in vivo__ pharmacokinetics and pharmacodynamics of both enantiomers are reported to be different. In the preparation of evaluation studies of both enantiomers in animals and humans, the pur

Synthesis and pet studies of [11C]D- and

Synthesis and pet studies of [11C]D- and [11C]L-boronophenylalanine for improving BNCT in brain tumors

✍ A. Studenov; Y.-S. Ding; R. Ferrieri; M. Miura; J. Coderre; J. S. Fowler 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 160 KB

Studies in the synthesis of C ring bridg

Studies in the synthesis of C ring bridged morphinans. 2. The synthesis and structural verification of a novel 3,11c-ethano-10-hydroxy-6-methyl-1,2,3,3a,11b,11c-hexahydroaporphine

✍ Roche, Edward B.; Nagel, Donald L.; McPhail, Andrew T. 📂 Article 📅 1984 🏛 American Chemical Society 🌐 English ⚖ 922 KB