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Synthesis and PET imaging of the benzodiazepine receptor tracer [N-methyl-11C]iomazenil

โœ Scribed by Ronald M. Baldwin; Andrew G. Horti; J.Douglas Bremner; Morgan D. Stratton; Robert F. Dannals; Hayden T. Ravert; Yolanda Zea-Ponce; Chin K. Ng; Holley M. Dey; Robert Soufer; Dennis S. Charney; Samuel M. Mazza; Richard B. Sparks; James B. Stubbs; Robert B. Innis


Book ID
116172011
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
683 KB
Volume
22
Category
Article
ISSN
0969-8051

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Quantitation of the PET benzodiazepine receptor antagonist, [ 11 C]Iomazenil, using low specific activity radioligand was recently described. The purpose of this study was to quantitate benzodiazepine receptor binding in human subjects using PET and high specific activity [ 11 C]Iomazenil. Six healt