Synthesis and optical resolution of high affinity P2-ligands for HIV-1 protease inhibitors
β Scribed by Arun K. Ghosh; Yan Chen
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 199 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A series of hydroxyethylpiperazine HIV-1 protease inhibitors containing various monocyclic or bicyclic thienylmethyl substituents as Py ligands were prepared. They were found to exhibit extremely high potency in the enzyme inhibition assay. These inhibitors also proved to be highly effective against
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