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Synthesis and neurotropic activity of silyl propargyl alcohols and sulfides

โœ Scribed by Ramona Abele; Liga Zvejniece; Edgars Abele; Kira Rubina; Pavel Arsenyan; Marina Vandish; Olga Pudova; Maija Dambrova; Ilona Domracheva; Irina Shestakova; Juris Popelis; Edmunds Lukevics

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
118 KB
Volume
18
Category
Article
ISSN
0268-2605

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โœ E. Lukevics; P. Arsenyan; S. Germane; I. Shestakova ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 37 KB

Neurotropic and antitumor activities of the pyridyl-substituted 5-Si(Ge)-isoxazolines and (3alkyl-4-triphenylgermylisoxazolin-2-yl)-5-carboxylic acid ethyl esters have been investigated. It has been shown that silylisoxazolin-2-yl derivatives are more potent in protection against hypoxia and Corazol