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Synthesis and Miscoding Specificity of Oligodeoxynucleotide Containing 8-Phenyl-2‘-deoxyguanosine

✍ Scribed by Kohda, Kohfuku; Tsunomoto, Hirotaka; Kasamatsu, Toshio; Sawamura, Fumiko; Terashima, Isamu; Shibutani, Shinya


Book ID
126431366
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
355 KB
Volume
10
Category
Article
ISSN
0893-228X

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## Abstract 8‐[^18^O]Hydroxy‐2′‐deoxyguanosine was synthesized starting from 8‐bromo‐2′‐deoxyguanosine and the sodium salt of [^18^O]benzyl alcohol, resulting in the intermediate 8‐[^18^O]benzyloxy‐2′‐deoxyguanosine. Subsequent reduction by catalytic transfer hydrogenation, yielded the desired prod