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Synthesis and mass spectrometry of deuterated methadone and methadone metabolites

✍ Scribed by Gun Ii Kang; Frank S. Abbott; Roland Burton


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
555 KB
Volume
6
Category
Article
ISSN
1076-5174

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The preparation of tritium labeled metha
✍ Herbert H. Seltzman; Steven D. Wyrick; Colin G. Pitt πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 430 KB

## Abstract The synthesis and catalytic tritium reduction of 1,2‐dehydro analogs of (‐)‐methadol, (‐)‐α‐acetylmethadol, and (‐)‐α‐acetyl‐N‐normethadol afforded the labeled compounds with high specific activity (44‐60 Ci/ mmole). The use of the homogeneous catalyst (Ο•~3~P)~3~RhCl resulted in specifi