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Synthesis and mass spectral studies of 1-[5-chloro-1-substituted-2(1H)-pyrazin-2-on-3-yl]-5-aryl-3-methylpyrazoles

✍ Scribed by B. K. Bhattacharya; F. R. Eirich


Book ID
112127770
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
334 KB
Volume
22
Category
Article
ISSN
0022-152X

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## Abstract Ketene generated from acetyl chloride or chloroacetyl chloride adds on indolyl Schiff's base double bond to afford 1‐butyl‐3‐substituted‐4‐(2‐aryl‐1__H__‐indol‐3‐yl)‐2‐azetidinones in THF. The reaction proceeds stereospecifically via concerted __trans__ [2+2] cycloaddition. The synthesi