𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and in vivo evaluation of [18F]ORG 13063, a potential pet radioligand for the 5-HT1A receptor

✍ Scribed by M. Vandecapelle; F. De Vos; H. Vermeirsch; K. Strijckmans; D. Leysen; K. Audenaert; R. A. Dierckx; G. Slegers

Book ID
112132878
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
250 KB
Volume
44
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

p-[18F]-MPPF: A potential radioligand fo
p-[18F]-MPPF: A potential radioligand for PET studies of 5-HT1A receptors in humans
✍ Chyng-Yann Shiue; Grace G. Shiue; P. David Mozley; Mei-Ping Kung; Zhi-Ping Zhuan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 2 views

The purpose of this study was to develop a radiopharmaceutical that could be used to selectively image 5-HT 1A receptors with positron emission tomography (PET). No-carrier-added 4-(28-methoxyphenyl)-1-[28-(N-29-pyridinyl)-p-[ 18 F]fluorobenzamido]ethylpiperazine ( p-[ 18 F]-MPPF, 2) was synthesized

Synthesis and preliminary in vivo evalua
Synthesis and preliminary in vivo evaluation of 4-[18F]fluoro-N-{2-[4-(6-trifluoromethylpyridin-2-yl)piperazin-1-yl]ethyl}benzamide, a potential PET radioligand for the 5-HT1A receptor
✍ M. Vandecapelle; F. Dumont; F. De Vos; K. Strijckmans; D. Leysen; K. Audenaert; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 138 KB 👁 1 views

## Abstract 4‐Fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)piperazin‐1‐yl]ethyl}benzamide is a full 5‐HT~1A~ agonist with high affinity (__pK__~__i__~=9.3), selectivity and a __c__ log __P__ of 3.045. The corresponding PET radioligand 4‐[^18^F]fluoro‐__N__‐{2‐[4‐(6‐trifluoromethylpyridin‐2‐yl)

Evaluation of 5-[18F]Fluoropropylepidepr
Evaluation of 5-[18F]Fluoropropylepidepride as a potential pet radioligand for imaging dopamine D2 receptors
✍ Robert M. Kessler; John R. Votaw; Tomas de Paulis; Daniel R. Bingham; M. Sib Ans 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 875 KB

## Abstract This study evaluated the utility of __(S)‐N__‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(3‐[^18^F]fluoropropyl)‐2,3‐dimethoxybenzamide ([^18^F]fluoropropylepidepride), [^18^F]5‐FPrEpid, as a ligar d for PET studies of cerebral dopamine D2 receptors. The in vitro affinity for the rat striatal d