𝔖 Bobbio Scriptorium
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Synthesis and in vitro transdermal penetration enhancing activity of lactam N-acetic acid esters

✍ Scribed by Bozena B. Michniak; Mark R. Player; J. Walter Sowell; Sr.


Book ID
109388431
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
132 KB
Volume
85
Category
Article
ISSN
0022-3549

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Series of N-substituted diethyl aspartates and Nsubstituted-3-oxo-l,4-piperazine-2-acetic acid esters were synthesized as potential inhibitors of aspartate transcarbamoylase. The aspartates were obtained by addition of substituted alkyl amines to diethyl maleate, or conversion of the hydroxy ethyl a