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Synthesis and in vitro Selective anti-Helicobacter pylori Activity of Pyrazoline Derivatives.

✍ Scribed by B. Bizzarri; et al. et al.


Publisher
John Wiley and Sons
Year
2005
Weight
16 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis and anti-Helicobacter pylori a
✍ Franco Chimenti; Bruna Bizzarri; Adriana Bolasco; Daniela Secci; Paola Chimenti; πŸ“‚ Article πŸ“… 2010 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 99 KB

## Abstract magnified image A novel class of coumarin‐thiazole conjugated systems (1‐31) were synthesized by Hantzsch condensation between α‐bromo‐3‐acetyl coumarin and several thiosemicarbazone intermediates. This scaffold was also evaluated for selective antibacterial activity against 20 isolates