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Synthesis and in vitro evaluation of boronated uridine and glucose derivatives for boron neutron capture therapy.

✍ Scribed by Tjarks, Werner; Anisuzzaman, Abul K. M.; Liu, Liang; Soloway, Albert H.; Barth, Rolf F.; Perkins, Douglas J.; Adams, Dianne M.


Book ID
120417397
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
884 KB
Volume
35
Category
Article
ISSN
0022-2623

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3, -p-carborane-l-yl)propyl]-6-phenyl phenanthridinium chloride hydrochloride (13) has been synthesised by reacting 3,8-diacetamido-6-phenylphenanthridine ) in nitrobenzene at 120Β°C for 4 days and subsequent removal of the protective groups using 33% HBr/AcOH. Conversion to the chloride hydrochlori