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Synthesis and in vitro evaluation of [18F]BMS-754807: A potential PET ligand for IGF-1R

✍ Scribed by Majo, Vattoly J.; Arango, Victoria; Simpson, Norman R.; Prabhakaran, Jaya; Kassir, Suham A.; Underwood, Mark D.; Bakalian, Mihran; Canoll, Peter; John Mann, J.; Dileep Kumar, J.S.

Book ID
120600919
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
494 KB
Volume
23
Category
Article
ISSN
0960-894X

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## Abstract A one‐step ^18^F‐labelling strategy was used to prepare four ^18^F‐labelled analogues of 7‐methoxy‐1‐methyl‐__9H__‐β‐carboline (harmine): 7‐(2‐[^18^F]fluoroethoxy)‐1‐methyl‐9__H__‐β‐carboline (5), 7‐(3‐[^18^F]fluoro‐propoxy)‐1‐methyl‐9__H__‐β‐carboline (6), 7‐[2‐(2‐[^18^F]fluoroethoxy)e