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Synthesis and in vitro cytotoxic evaluation of 2-hydrazinylpyrido[2,3-b]pyrazin-3(4H)-one derivatives

✍ Scribed by Guo Gang Zhang; Ya Jing Liu; Xiao Guang Ma; Hao Dong; Ju Li; Ping Gong

Book ID
113523189
Publisher
Chinese Electronic Periodical Services
Year
2011
Tongue
English
Weight
167 KB
Volume
22
Category
Article
ISSN
1001-8417

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## Abstract In an attempt to develop potent antitumor agents, a series of novel 2‐hydrazonylpyrido[2,3‐__b__]pyrazin‐3(4__H__)‐one derivatives were designed and synthesized. All the prepared compounds were screened for their cytotoxic activities against A549, MDA‐MB‐231 and HT‐29 cell lines __in vi