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Synthesis and In Vitro Biological Properties of Novel Cationic Derivatives of Amphotericin B

✍ Scribed by Valérie Paquet; Astrid A. Volmer; Erick M. Carreira

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
448 KB
Volume
14
Category
Article
ISSN
0947-6539

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HPLC assay for determination of amphoter
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✍ R. Espada; J. M. Josa; S. Valdespina; M. A. Dea; M. P. Ballesteros; J. M. Alunda 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 2 views

## Abstract A fast and selective HPLC method for assaying amphotericin B in biological samples was developed and validated. The chromatographic separation was achieved in less than 12 min on a reverse‐phase C~18~ column using an acetonitrile–acetic acid–water (52:4.3:43.7, v/v/v) mixture as mobile