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Synthesis and in vitro antitumor activity of some triarylantimony di(N-phenylglycinates)

✍ Scribed by Lin Yu; Yong-Qiang Ma; Guo-Cang Wang; Jin-Shan Li


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
92 KB
Volume
15
Category
Article
ISSN
1042-7163

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✦ Synopsis


Triarylantimony(V) di(N-phenylglycinates) (PhNHCH 2 COO) 2 SbAr 3 (Ar = Ph, p-CH 3 C 6 H 4 , p-ClC 6 H 4 , and p-FC 6 H 4 ) have been synthesized and characterized by elemental analysis, IR, 1 H NMR, and mass spectra. The crystal structure of (PhNHCH 2 COO) 2 Sb(C 6 H 4 F-p) 3 has been determined by X-ray diffraction. The in vitro antitumor activities of these compounds against three cancer cell lines are reported.


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