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Synthesis and In Vitro Antitumor Activity of New Substituted Thiopyrimidine Acyclic Nucleosides and Their Thioglycoside Analogs

✍ Scribed by El-Sayed, Wael A.; Rashad, Aymn E.; Awad, Samir M.; Ali, Mamdouh M.


Book ID
120024958
Publisher
Taylor and Francis Group
Year
2009
Tongue
English
Weight
362 KB
Volume
28
Category
Article
ISSN
0732-8311

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Synthesis and antitumor activity of new
✍ Wael A. El-Sayed; Ibrahim F. Nassar; Adel A.-H. Abdel-Rahman 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 167 KB

## Abstract New 1,2,4‐triazine and their derived 1,2,4‐triazolo[3,4‐__b__][1,2,4]triazine derivatives were synthesized starting from 5,6‐diphenyl‐1,2,4‐triazine‐3‐thiol. Furthermore, the corresponding 1,2,4‐triazolo[3,4‐__b__][1,2,4]‐triazine thioglycosides and acyclic __C__‐nucleoside analogs were