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Synthesis and in vitro antibacterial activity of 7-(3-Alkoxyimino-4-amino-4-methylpiperidin-1-yl) fluoroquinolone derivatives

โœ Scribed by Ju-Xian Wang; Yi-Bin Zhang; Ming-Liang Liu; Bo Wang; Yun Chai; Su-Jie Li; Hui-Yuan Guo


Book ID
108116586
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
383 KB
Volume
46
Category
Article
ISSN
0223-5234

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Synthesis and in vitro antibacterial act
โœ Yibin Zhang; Guoqing Li; Mingliang Liu; Xuefu You; Lianshun Feng; Kai Lv; Jue Ca ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 438 KB

We report herein the design and synthesis of novel 7-(3-alkoxyimino-5-amino/methylaminopiperidin-1yl)fluoroquinolone derivatives based on the structures of new fluoroquinolones IMB and DZH. The antibacterial activity of these newly synthesized compounds was also evaluated and compared with gemifloxa