✦ LIBER ✦

Synthesis and in vitro activity of stereoisomers of a novel thromboxane receptor antagonist, (.+-.)-(5Z)-7-[(3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1]hept-2-exo-yl]heptenoic acid

✍ Scribed by Ohtani, Mitsuaki; Narisada, Masayuki

Book ID: 126258507
Publisher: American Chemical Society
Year: 1990
Tongue: English
Weight: 704 KB
Volume: 33
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00165a022

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Characterization of (5Z)-7-[3-endo-[(4-i

Characterization of (5Z)-7-[3-endo-[(4-iodophenylsulfonyl) amino]-bicyclo[2.2.1]hep-2-exo-yl]heptenoic acid (IS-145) as an antagonist for the study of thromboxane A2 receptor

✍ Kan, W.M.; Tai, H.H. 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 681 KB

Synthesis of dl-cis- and (4R,5R)-trans-7

Synthesis of dl-cis- and (4R,5R)-trans-7-[2,2-dimethyl-4-(phenylsulfonyl)-aminomethyl-1,3-dioxolan-5-yl]-5(Z)-heptenoic acid analogues as platelet thromboxane A2 receptor antagonist

✍ D Komiotis; S PananookoolnJ; K Zaw; JP Dieter; GC Le Breton; DL Venton 📂 Article 📅 1995 🏛 Elsevier Science 🌐 French ⚖ 723 KB

Improved synthesis of (5Z)-7-(3-endo-{(b

Improved synthesis of (5Z)-7-(3-endo-{(benzenesulfonamido)-bicyclo[2.2.1]heptyl}hept-5-enoic acid (S-145) derivatives and their iodine-125-labeled radioligands for the study of thromboxane A2 receptor

✍ Wai Ming Kan; Hsin-Hsiung Tai 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 567 KB

An improved synthetic scheme for (5Z)-7-[3-endo-[(benzenesulfonamido)-bicyclo[2.2.1]heptyl I-hept-5-enoic acid (S145) and its analogs has been designed. The procedure involves direct sulfonylation of 2-allyl-3-aminobicyclo[2.2. l]heptane intermediate followed by ozonolysis and addition of a C5 carbo

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Evaluation of Novel 9-Heteroaryl Substituted 7-Chloro-4,5-dihydro-4-oxo-1,2,4-triazolo [1,5-a]quinoxaline-2-carboxylates (TQX) as (R,S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptor Antagonists.

✍ Daniela Catarzi; Vittoria Colotta; Flavia Varano; Guido Filacchioni; Paola Gratt 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 45 KB 👁 1 views