Synthesis and Identification of a Novel 6,5,6-Tricyclic Lactam.
β Scribed by Joel P. Cooper; Jeff E. Cobb; Barry G. Shearer; Douglas J. Minick; Randy D. Rutkowske
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 131 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The stereoselective synthesis of two precursors of tricyclic Ξ²-ring-forming reaction followed by the reduction of a functionalized aromatic substituent at C-4 of the Ξ²-lactam lactam antibiotics (trinems) has been attempted by a novel approach that involves a highly stereoselective azetidinone nucleu
GV118819X, a novel tricyclic β€-lactam antibiotic of GlaxoWellcome, is a racemic mixture of two diastereoisomers, A and B. Of the two diastereoisomers, only A is available as a pure compound. By analyzing mixtures of GV118819X and A, a partial phase diagram is constructed, which indicates the presenc