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Synthesis and Hypolipidemic Activities of Novel 2-[4-[(Diethoxyphosphoryl)methyl]phenyl]quinazolines and 4(3 H )-Quinazolinones

✍ Scribed by Kurogi, Yasuhisa; Inoue, Yasuhide; Tsutsumi, Kazuhiko; Nakamura, Shizuo; Nagao, Kazushi; Yoshitsugu, Hiroki; Tsuda, Yoshihiko


Book ID
118739901
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
154 KB
Volume
39
Category
Article
ISSN
0022-2623

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Solid-phase synthesis of 3,4-dihydro-2(1
✍ Qun Sun; Xiaoming Zhou; Donald J Kyle πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 113 KB

The solid-phase synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones is described. Starting from Rink resin, acylation with 4-bromomethyl-3-nitrobenzoic acid and amination with primary amines, reduction with tin chloride and cyclization, the desired 3,4-dihydro-2(1H)